Effects of High Fat Diet Induced Obesity on Female Rat Livers (a Histochemical Study)

Obesity is a severe metabolic disorder, characterized with increases in energy intake and a decrease in energy output concerning body weight and glucose metabolism (1) Obesity is associated with many important complications such as diabetes and coronary heart disease (2) sleep apnea and pulmonary dysfunction, stroke, diseases of the gallbladder, liver and the musculoskeletal system, reproductive dysfunction, venous insufficiency, deep vein thrombosis, poor wound healing, and more (3). Ramos et al. thought that obesity should be a low-grade inflammatory disease because most of the obese patients had shown increased levels of interleukin-6 and tumor necrosis factor-alpha, both markers of inflammation (4). Obesity may be the underlying reason of cancers of the breast, endometrium, colon and prostate. Obesity is an increasing problem EFFECTS OF HIGH FAT DIET INDUCED OBESITY ON FEMALE RAT LIVERS (A HISTOCHEMICAL STUDY)